1
Place the era board
Set up the Mariners, Planeteers, or Starfarers board matching the chosen era
2
Set up discovery tiles (Mariners/Planeteers)
Place 6/6 era 1, 3/14 era 2, and 0/8 era 3 discovery tiles randomized on matching board spaces
3
Place Beyond markers (Mariners/Planeteers)
Put 1st and 2nd Beyond markers on matching board spaces
4
Set up discovery stacks (Starfarers)
Shuffle 16 Primary into 2 stacks of 8, 12 Secondary into 2 stacks of 6, and 5 Alien tokens as 5 separate discovery stacks
5
Place Business Display
Position the Contract Fulfilled orange discs on their starting spaces
6
Place Sideboard Display (Mariners/Planeteers only)
Use the back of the Mariners map
7
Set up Adaptation and Breakthrough cards
Place 16 Adaptation (Genetics) and Breakthrough (Revelation) cards in stacks matching names with $ (VP) on top
8
Place Colony tiles (Starfarers)
Set out 12 (2-player), 17 (3-player), or 20 (4-player) Colony tiles on matching sideboard spaces
9
Take player HQ
Each player takes an HQ board matching the chosen era
10
Place Profit marker
Put matching Profit marker on Business Display space "0" (exception: last player starts at "1" in 3-4 player games)
11
Place Base markers
Put 9×3 matching Base round markers on HQ Board matching spaces
12
Place Team cubes
Put 2 (Starfarers: 3) matching Team cubes on the Base space on the game board
13
Set up 1st/2nd Beyond players (Planeteers)
1st Beyond sets up on Ceres and explores free; 2nd Beyond sets up on Vesta unexplored
14
Set up 1st/2nd Beyond players (Starfarers)
1st Beyond sets up on Alpha Centauri star; 2nd Beyond sets up on Luhman 16 leftmost box
15
Place Progress cubes
Put 1 Genetics tan cube and 1 Revelation black cube on top of HQ's Progress Wheel (later eras: leave in place)
16
Set aside Start cards
Remove 12 era "Start" cards from the deck
17
Prepare draw deck
Add 0/2/4 Time cards (for 2/3/4 players) plus current era deck and shuffle
18
Prepare starting hand (Mariners)
Take 1 Time card and 1 Chemical Drive "Mariners Start" card
19
Prepare starting hand (Planeteers/Starfarers)
Take 1 Time card and 2 random era-matching Start cards
20
Shuffle remaining Start cards
Place remaining Start cards on top of the draw deck
21
Determine Start Player (Mariners)
Player who last gazed at night sky goes first; in 2-player 2nd gets +1 card; in 3-player 2nd and 3rd get +1 card; in 4-player 3rd and 4th get +1 card; last player gets +1$ in 3-4 player games
22
Determine Start Player (Planeteers/Starfarers)
Previous 1st Beyond player, then least Profit, then random
23
Fill Card Offer
Place cards in the Card Offer spaces on the game board